So Much for the Germ Theory: Scientists Demonstrate That Sleep Matters More Than Germs

More in a continuing series about one of my favorite topics, something we all do every day, and spend roughly a third of our lives doing…sleep!

Since we are in the middle of the common cold season, this post will be particularly relevant.

It turns out, grandma was right. Getting good sleep really does prevent colds. This supports a favorite belief of mine—that I don’t believe in the germ theory of illness.  Read on and you will see why I liked the referenced article.

Researchers at a variety of universities collaborated and did a clever study looking at sleep and its effects on susceptibility to the common cold. First they had their 153 subjects, healthy men and women between 21 and 55, report their sleep duration and efficiency for 2 weeks. (Efficiency is what percent of the time you are actually sleeping while in bed.) Next, these diabolical researchers sprayed cold virus up the noses of all the subjects (in quarantine), and watched what happened over the next 5 days.

The results were very interesting. Those subjects who slept less than 7 hours were almost 3 times more likely to develop a cold than those who slept 8 hours or more. In addition, those whose sleep was less than 92% efficient were 5.5 times more likely to develop a cold than those with 98% or more sleep efficiency. Interestingly, how rested subjects reported feeling after sleep was not associated with colds.  The lead author of the study concluded, “The longer you sleep, the better off you are, the less susceptible you are to colds.”

Now I promised that I would report evidence that this study bolsters my theory that germs don’t really matter that much. Remember the researchers sprayed virus up everyone’s noses. After five days, the virus had infected 135 of 153 people, or 88% of the people, but only 54 people (35%) got sick. What this suggests is that even among the people who were infected with cold virus, 60% stayed healthy, while 40% got sick. And the ones who got sick were much more likely to have reported less and lower quality sleep in the two weeks before infection. 

This is very relevant for everyday life, since much of the time we can’t really avoid exposure to common germs like colds and flu. If good sleep protects us even when infected with such germs, then it may be the key to staying healthy.

What is truly fascinating about this study is the precise immune regulation showed by those who got infected, but stayed healthy. To understand this let me digress for a moment with a short primer on the common cold. Most people think cold symptoms are caused by cold virus. This is wrong. Actually, cold symptoms are caused by our bodies’ immune reaction to the cold virus. Our bodies produce germ fighting proteins called cytokines, and when our bodies make too much, we get the congestion and runny nose symptoms. If our bodies make just the right amounts of cytokines, we fight the virus without feeling sick.

So getting 8 or more hours of sleep a night may allow your body to fine tune an immune response, and make just the perfect amount of germ fighting proteins.

Another interesting finding is the relationship of sleep efficiency and illness. Sleep efficiency was an even more powerful predictor of getting sick than total sleep. (Of course, this might reflect an overall difference in sleep quality. Those who sleep deeply may tune up their immune systems better, and they are likely to spend most of their time in bed asleep.)

But assuming that increasing sleep efficiency is useful, then those people who take a long time to fall asleep, and who sleep fitfully may benefit from spending less time in bed, and working on sleeping more of the time they are in bed. On the other hand, those who fall asleep as soon as their head hits the pillow, and who are sleep like logs, would probably benefit from spending a little more time in bed, since they are not getting enough sleep.

So there you have it. Sleep 8 hours or more, try to sleep well, and you can lower your odds of getting a cold greatly. Even if you are exposed to the virus, if you have good sleep quality, you probably won’t get sick. So much for the simple germ theory! I suspect that this applies to all infectious diseases. So getting good quality and quantity in sleep may be one of the most important health behaviors for staying well.

It’s late, and I’m off to bed now…..zzzzzzzzzzzzzzz.

Copyright © 2009 The Psychology Lounge/TPL Productions/Andrew Gottlieb

Good News and Bad News for Chocolate Lovers

There is good news and bad news today for chocolate lovers, especially those who love dark chocolate. The good news is that small amounts of dark chocolate may be very good for your heart.

A very nice study was published today that shows that a fairly small amount of dark chocolate has a powerful impact on C-reactive protein, which is a blood marker of inflammatory processes in the body. This protein is a powerful predictor of heart disease. Higher levels of C-reactive protein indicate chronic inflammation in the body which leads to more risk of cardiovascular disease.

Scientists at the Research Laboratories of the Catholic University in Campobasso, working with the national Cancer Institute of Milan conducted a large scale study of 20,000 people that examined the intake of dark chocolate and found that those people who eat moderate amounts of dark chocolate regularly have C-reactive protein levels 17% lower than those who do not consume dark chocolate. This seems like a small difference, but it correlates with a decrease in cardiovascular disease of one third in women and one fourth in men. This is actually a very significant finding.

So what’s the bad news? The bad news is the quantity of dark chocolate the researchers found optimum. The best effect was obtained by consuming an average amount of 6.7 grams of chocolate per day. Since the typical bar of dark chocolate is 100 grams that means the optimum dose of dark chocolate would be obtained by eating four small squares of chocolate per week. This means eating half a bar of chocolate per week, or roughly one small square every two days. So that’s the bad news, you have to limit your dark chocolate in order to benefit maximally. In this study they found those who ate more than this amount lost most of the benefits. So a little is good but more is not better!

By the way, the researchers adjusted for many other factors, and are confident that the dark chocolate had an impact directly. And for those who prefer milk chocolate, I am sorry, there was no benefit shown to eating milk chocolate.

As one of the lead researchers,  Giovanni de Gaetano, director of the Research Laboratories of the Catholic University of Campobasso, said, “Maybe time has come to reconsider the Mediterranean diet pyramid and take the dark chocolate off the basket of sweets considered to be bad for our health”. So that’s the good news, you can eat dark chocolate in moderation, without guilt. The bad news is that you have to stop after one small square!

I’ve got to go now, as I’ve got a lovely Le Noir Extra Amer 85% Cacao bar of Dark Bitter Chocolate waiting for me…

Copyright © 2008 The Psychology Lounge/TPL Productions

All Rights reserved (Any web links must credit this site, and must include a link back to this site.)

How to Live a Long Healthy Life (for Men only)

The New York Times had an excellent article looking at a recent study that suggests that the secret to living past 90 may be found in five simple behaviors. The study, performed at Brigham and Women’s Hospital in Boston followed 2300 healthy men for 25 years. The average age at the beginning was 72. By the end of the study, 970 men had survived into their 90’s.

The key behaviors that were associated with longevity were not smoking, keeping a healthy weight, controlling blood pressure, getting regular exercise, and preventing diabetes.

The results?

“There was no less chronic illness among survivors than among those who died before 90. But after controlling for other variables, smokers had double the risk of death before 90 compared with nonsmokers, those with diabetes increased their risk of death by 86 percent, obese men by 44 percent, and those with high blood pressure by 28 percent. Compared with men who never exercised, those who did reduced their risk of death by 20 percent to 30 percent, depending on how often and how vigorously they worked out.”

So there you have it. First stop smoking, or don’t start. Second, control your weight and eating patterns to avoid Type 2 diabetes. Third, lose weight so that you are not obese. Control your blood pressure, and exercise, and you’ve got longevity nailed. What is interesting is that although smoking is a completely independent risk factor, the other four are highly related to something called Syndrome X, a metabolic syndrome that is associated with high levels of blood sugar and insulin production, which leads to weight gain, hypertension, and pre-diabetes. Exercise leads to weight loss, and independently reduces the tendency to Syndrome X.And it’s not too late. Since the study only looked at these five behaviors after age 72, even change that occurs late in life can greatly extend and improve life.

Unfortunately, since the study only included men, we can’t really generalize the results to women, but it is likely that the same principles apply.

And now, I have to go take a swim…

Copyright © 2008 The Psychology Lounge/TPL Productions

All Rights reserved (Any web links must credit this site, and must include a link back to this site.)